THE SCIENCE · U 2.0

Ingredient science, presented clearly.

Choose a formula to explore its individual ingredients, disclosed amounts, and the research that has been conducted on them.

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This page summarises published research on individual ingredients. It describes what has been studied about these ingredients in general, published research — it does not describe the effects of U 2.0 as a finished product, and no medical, health or performance claim about U 2.0 is made or implied.

BOTANICAL RESEARCH

Ashwagandha

Withania somnifera

180 mg9 mg withanolides · 5%

What it is

Ashwagandha is a botanical root extract traditionally used in Ayurvedic practice and studied in a range of human research settings.

Why it's included

Included as part of the botanical formulation. The research summary below is about ashwagandha as an individual ingredient, not the finished U 2.0 product.

What the research says

An 8-week randomised, double-blind, placebo-controlled trial in overweight men (Lopresti et al., 2019) is described as using 300 mg twice daily and recording changes in DHEA-S and testosterone alongside wellbeing measures. A separate 8-week trial in resistance-trained men (Wankhede et al., 2015) is described as using 600 mg/day and reporting greater strength gains and a larger serum-testosterone increase versus placebo. The cited studies should be read in the context of the individual ingredient and study population.

Source / citation: Lopresti et al. (2019) — citation details are provided where available; Wankhede et al. (2015) — citation details are provided where available.

BOTANICAL RESEARCH

Shilajit

Purified shilajit

300 mg60 mg fulvic acid · 20%

What it is

Shilajit is a naturally occurring mineral-rich substance traditionally used in Ayurvedic practice and supplied here as a purified extract.

Why it's included

Included as one of the disclosed botanical ingredients in the Male formula.

What the research says

A 90-day randomised, double-blind, placebo-controlled trial in healthy volunteers aged 45–55 (Pandit et al., 2016, published in Andrologia) using purified shilajit at 250 mg twice daily and reporting significant changes in total and free testosterone versus placebo. The cited study concerns the individual ingredient, not the finished U 2.0 product.

Source / citation: Pandit et al. (2016), Andrologia — original paper and citation.

BOTANICAL RESEARCH

Fenugreek

Trigonella foenum-graecum

300 mg150 mg saponins · 50%

What it is

Fenugreek is a legume whose seeds have a long history of culinary and traditional use and are used here as a standardised botanical extract.

Why it's included

Included as a disclosed botanical extract within the Male formulation.

What the research says

Randomised, placebo-controlled trials using standardised fenugreek extract at approximately 600 mg/day in healthy men. It reports improvements in self-reported libido and, in some but not all trials, small increases in free testosterone, while total-testosterone findings are described as less consistent. The individual trials and citations should be re-verified.

Source / citation: Standardised fenugreek human trials — the relevant study details are reported in the cited research.

BOTANICAL RESEARCH

Rhodiola Rosea

Rhodiola rosea root

100 mg3 mg rosavins + 1 mg salidroside · 10:1

What it is

Rhodiola rosea is a botanical root traditionally used in herbal preparations and supplied here as a standardised root extract.

Why it's included

Included as one of the disclosed botanical ingredients in the Male formula.

What the research says

A systematic review of randomised controlled trials on Rhodiola rosea for fatigue (Ishaque et al., 2012). It describes the overall evidence as contradictory, with some trials reporting improvements on fatigue or mental-performance measures and others finding no significant effect versus placebo. This mixed evidence should remain explicit.

Source / citation: Ishaque et al. (2012) — systematic review citation should be verified against the original publication.

BOTANICAL RESEARCH

Maca

Lepidium meyenii

100 mg10:1 extract

What it is

Maca is a Peruvian root crop with a long history of traditional food and botanical use.

Why it's included

Included as a disclosed botanical extract within the Male formulation.

What the research says

Randomised controlled trials in men (Gonzales et al.) reporting improvements in self-reported sexual desire with maca versus placebo, while noting that these trials did not show a corresponding increase in serum testosterone. The cited studies concern the individual ingredient and their reported study populations.

Source / citation: Gonzales et al. — published maca studies.

BOTANICAL RESEARCH

Pomegranate

Punica granatum

200 mg80 mg ellagic acid · 40%

What it is

Pomegranate is a fruit botanical rich in naturally occurring polyphenols, including ellagic acid.

Why it's included

Included for its disclosed botanical profile within the Male formulation.

What the research says

Pomegranate extract has been studied mainly for antioxidant and cardiovascular markers, with more limited evidence specific to men's hormonal or performance outcomes. It cites exercise-recovery research such as Trombold et al. (2011), while stating that the ingredient is included primarily for its antioxidant profile. The original citation describes the individual ingredient research.

Source / citation: Trombold et al. (2011) — original publication and citation.

BOTANICAL RESEARCH

Black Pepper Extract

Piper nigrum · piperine

5 mg4.75 mg piperine · 95%

What it is

Black pepper extract is a botanical extract standardised here for piperine, a naturally occurring constituent of black pepper.

Why it's included

Included as a formulation ingredient and described in relation to research on bioavailability enhancement.

What the research says

Research describes piperine as a bioavailability enhancer and cites research such as Shoba et al. (1998) involving curcumin. It specifically says piperine should not be presented as having a standalone health effect of its own.

Source / citation: Shoba et al. (1998) — original publication and citation.

BOTANICAL RESEARCH

Ginger

Zingiber officinale

50 mg20:1 extract

What it is

Ginger is a culinary and botanical root used in traditional preparations and supplied here as a concentrated root extract.

Why it's included

Included as one of the disclosed botanical ingredients in the Male formulation.

What the research says

Ginger has been studied for anti-inflammatory and antioxidant activity in various contexts, while evidence specific to testosterone or male hormonal outcomes is limited. No product-level hormonal claim is made here.

Source / citation: A single definitive citation is not provided here for this ingredient.

AUTHORISED NUTRIENT

Zinc

Zinc citrate

10 mg100% NRV

What it is

Zinc is an essential mineral supplied in the formula as zinc citrate.

Why it's included

Included as a disclosed mineral nutrient in the Male formulation.

Authorised nutrient function

Zinc contributes to the maintenance of normal testosterone levels in the blood. This is an authorised nutrient claim when the applicable conditions of use are met.

Source / citation: Authorised nutrient claim: zinc contributes to the maintenance of normal testosterone levels in the blood.

AUTHORISED NUTRIENT

Vitamin D3

Vitamin D

50 mcg1000% NRV

What it is

Vitamin D is a fat-soluble vitamin supplied here as vitamin D3.

Why it's included

Included as a disclosed vitamin nutrient in the Male formulation.

Authorised nutrient function

Vitamin D contributes to the maintenance of normal muscle function and the normal function of the immune system, where the applicable conditions of use are met.

Source / citation: Authorised nutrient functions: vitamin D contributes to the maintenance of normal muscle function and the normal function of the immune system.

AUTHORISED NUTRIENT

Vitamin B6

Pyridoxal-5-phosphate

3.2 mg229% NRV

What it is

Vitamin B6 is a water-soluble B vitamin supplied in the formula as pyridoxal-5-phosphate.

Why it's included

Included as part of the disclosed B-vitamin and micronutrient foundation.

Authorised nutrient function

Vitamin B6 contributes to normal energy-yielding metabolism and the regulation of hormonal activity, where the applicable conditions of use are met.

Source / citation: Authorised nutrient functions: vitamin B6 contributes to normal energy-yielding metabolism and the regulation of hormonal activity.

AUTHORISED NUTRIENT

Folic Acid

Folate

192 mcg96% NRV

What it is

Folic acid is a form of folate, a B vitamin included in the formula as a disclosed micronutrient.

Why it's included

Included as part of the disclosed vitamin and mineral foundation.

Authorised nutrient function

Folic acid contributes to normal psychological function, the reduction of tiredness and fatigue, and normal homocysteine metabolism, where the applicable conditions of use are met.

Source / citation: Authorised nutrient functions: folic acid contributes to normal psychological function, the reduction of tiredness and fatigue, and normal homocysteine metabolism.

AUTHORISED NUTRIENT

Vitamin B12

Cobalamin

1 mcg40% NRV

What it is

Vitamin B12 is a water-soluble B vitamin included as a disclosed micronutrient.

Why it's included

Included as part of the disclosed B-vitamin foundation.

Authorised nutrient function

Vitamin B12 contributes to normal energy-yielding metabolism, normal functioning of the nervous system, normal psychological function, and the reduction of tiredness and fatigue, where the applicable conditions of use are met.

Source / citation: Authorised nutrient functions: vitamin B12 contributes to normal energy-yielding metabolism, normal functioning of the nervous system, normal psychological function, and the reduction of tiredness and fatigue.

AUTHORISED NUTRIENT

Vitamin K2

Menaquinone-7 (MK-7)

11.3 mcg15% NRV

What it is

Vitamin K2 is a form of vitamin K supplied here as menaquinone-7 (MK-7).

Why it's included

Included as a disclosed vitamin nutrient in the Male formulation.

Authorised nutrient function

Vitamin K contributes to normal blood clotting and the maintenance of normal bones, where the applicable conditions of use are met.

Source / citation: Authorised nutrient functions: vitamin K contributes to normal blood clotting and the maintenance of normal bones.

AUTHORISED NUTRIENT

Magnesium

Magnesium bisglycinate

56 mg15% NRV

What it is

Magnesium is an essential mineral supplied in the formula as magnesium bisglycinate.

Why it's included

Included as a disclosed mineral nutrient in the Male formulation.

Authorised nutrient function

Magnesium contributes to normal muscle function and the reduction of tiredness and fatigue, where the applicable conditions of use are met. It also contributes to normal protein synthesis and normal psychological function.

Source / citation: Authorised nutrient functions: magnesium contributes to normal muscle function, the reduction of tiredness and fatigue, normal protein synthesis, and normal psychological function.

FORMULATION

U 2.0 Men at a glance.

15 disclosed ingredients across botanical extracts, vitamins and minerals. Amounts below reflect the current project data used to build this page.

IngredientAmount / 3 capsulesStandardisation / NRV
Ashwagandha180 mg9 mg withanolides · 5%
Shilajit extract300 mg60 mg fulvic acid · 20%
Fenugreek extract300 mg150 mg saponins · 50%
Rhodiola rosea root extract100 mg3 mg rosavins + 1 mg salidroside · 10:1
Maca root extract100 mg10:1
Pomegranate fruit extract200 mg80 mg ellagic acid · 40%
Black pepper extract5 mg4.75 mg piperine · 95%
Ginger root extract50 mg20:1
Magnesium56 mg15% NRV
Zinc10 mg100% NRV
Vitamin D350 mcg1000% NRV
Vitamin B63.2 mg229% NRV
Folic acid192 mcg96% NRV
Vitamin B121 mcg40% NRV
Vitamin K211.3 mcg15% NRV

NRV = Nutrient Reference Value. Botanical ingredients do not carry an NRV. Confirm all Male formula amounts against the final approved Male TDS before publishing.

SCIENCE & EVIDENCE Authorised nutrient claims & botanical research

The sections below distinguish authorised nutrient functions from research on individual botanical ingredients. Botanical research is presented as research on the ingredient itself and is not a health, medical or performance claim for U 2.0 as a finished product.

AUTHORISED NUTRIENT CLAIMS

What the nutrients contribute to.

ZINC

Contributes to the maintenance of normal testosterone levels in the blood.

VITAMIN D3

Contributes to normal muscle function and normal immune function.

MAGNESIUM

Contributes to normal muscle function and the reduction of tiredness and fatigue.

VITAMIN B6

Contributes to normal energy-yielding metabolism and the regulation of hormonal activity.

IODINE

Contributes to normal cognitive function and normal thyroid function.

BOTANICAL RESEARCH SUMMARIES

What published research has explored.

Ashwagandha

An 8-week randomised, double-blind, placebo-controlled trial in overweight men (Lopresti et al., 2019) using 300 mg twice daily, and a separate 8-week trial in resistance-trained men (Wankhede et al., 2015) using 600 mg/day. The brief reports changes in DHEA-S, testosterone, wellbeing and strength outcomes and requires both citations to be verified against the original papers.

Shilajit

A 90-day randomised, double-blind, placebo-controlled trial in healthy volunteers aged 45–55 (Pandit et al., 2016, Andrologia) using purified shilajit at 250 mg twice daily. The brief reports significant changes in total and free testosterone versus placebo and cites a published study.

Fenugreek

Randomised, placebo-controlled trials using standardised fenugreek extract at approximately 600 mg/day in healthy men. It reports improvements in self-reported libido and, in some but not all trials, small increases in free testosterone, while total testosterone findings are described as less consistent.

Rhodiola rosea

A systematic review cited (Ishaque et al., 2012) is described as finding contradictory evidence overall for fatigue, with some trials reporting improvements on fatigue or mental-performance measures and others finding no significant effect versus placebo.

Maca

Randomised controlled trials in men (Gonzales et al.) reporting improvements in self-reported sexual desire versus placebo, while noting that these trials did not find a corresponding increase in serum testosterone.

Pomegranate

Pomegranate extract has been studied mainly for antioxidant and cardiovascular markers, with more limited evidence specific to men's hormonal or performance outcomes. It cites exercise-recovery research such as Trombold et al. (2011).

Black pepper extract & ginger

Research describes piperine in black pepper as a bioavailability enhancer and cites Shoba et al. (1998) on curcumin. Ginger is described as having been studied for anti-inflammatory and antioxidant activity, while evidence specific to testosterone or male hormonal outcomes is described as limited.

THE HUMANIX

Transparent formulation. Honest evidence.

U 2.0 is a food supplement. It should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. Always use the approved product warnings and conditions of use from the final product documentation.